Khalid Saifullah, PhD

Khalid Saifullah, PhD

Research Fellow @MGH & Harvard Medical School
Neuropathology | Neuroimaging | Machine Learning

Publications

You can also find my articles on my Google Scholar profile.

Journal Articles

Brain Morphometry Patterns in the Presence of Alzheimer’s Disease and/or LATE Neuropathologic Changes

Published in Alzheimer's & Dementia, 2026

Using deformation-based morphometry on ex vivo MRI from 912 community-based older adults, we identified distinct and overlapping brain morphometry patterns associated with Alzheimer’s disease and LATE neuropathologic changes.

Recommended citation: Saifullah K, Ridwan AR, Evia AM, et al. Brain morphometry patterns in the presence of Alzheimer’s disease and/or LATE neuropathologic changes. Alzheimer’s Dement. 2026;22:e71719. doi:10.1002/alz.71719.
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Neuropathological Correlates of Volume and Shape of Deep Gray Matter Structures in Community-Based Older Adults

Published in Human Brain Mapping, 2025

Using ex vivo MRI and autopsy data from 842 older adults (Rush Cohort), we mapped how common neuropathologies independently affect deep gray matter volume and shape.

Recommended citation: Saifullah K, Makkinejad N, Yasar MT, et al. Neuropathological Correlates of Volume and Shape of Deep Gray Matter Structures in Community-Based Older Adults. Hum Brain Mapp. 2025;46(10):e70273. doi:10.1002/hbm.70273.
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Journal Articles In Preparation / Submitted / Under Review

Conference Abstracts (Oral / Poster Presentations)

Older Age And Heart Disease Are Associated With A Faster Increase In ARTS

Published in Alzheimer's Association International Conference (AAIC), 2026

Poster Presentation

Recommended citation: Tomash, A., Saifullah, K., et al. Older Age And Heart Disease Are Associated With A Faster Increase In ARTS. Alzheimer's Association International Conference (AAIC) Annual Meeting, July 12-15, 2026, London, United Kingdom.

An MRI-Based Marker of Braak Stage

Published in Alzheimer's Association International Conference (AAIC), 2026

Poster Presentation

Recommended citation: Saifullah, K., et al. An MRI-Based Marker of Braak Stage. Alzheimer's Association International Conference (AAIC) Annual Meeting, July 12-15, 2026, London, United Kingdom.

Regional White Matter Hyperintensities and Age-Related Neuropathologies

Published in Organization for Human Brain Mapping (OHBM), 2026

Poster Presentation

Recommended citation: Chowdhury, G. M., Saifullah, K., et al. Regional White Matter Hyperintensities and Age-Related Neuropathologies. Organization for Human Brain Mapping (OHBM) Annual Meeting, June 14-18, 2026, Bordeaux, France.

Older Age and Heart Disease are Associated with a Faster Increase in ARTS

Published in Organization for Human Brain Mapping (OHBM), 2026

Poster Presentation

Recommended citation: Tomash, A., Saifullah, K., et al. Older Age and Heart Disease are Associated with a Faster Increase in ARTS. Organization for Human Brain Mapping (OHBM) Annual Meeting, June 14-18, 2026, Bordeaux, France.

Higher ARTS Score Is Associated with Higher Levels of NfL but Not with p-Tau217

Published in Radiological Society of North America (RSNA), 2025

Poster Presentation

Recommended citation: Chowdhury, G. M., Saifullah, K., et al. Higher ARTS Score Is Associated with Higher Levels of NfL but Not with p-Tau217. Poster Presentation, Radiological Society of North America (RSNA), 111th Scientific Assembly and Annual Meeting, Nov 30 - Dec 4, 2025, Chicago, IL, USA.

Plasma Neurofilament Light Reflects Brain Tissue Loss, Ventricular Enlargement, and Vascular-Mediated Neurodegeneration

Published in Radiological Society of North America (RSNA), 2025

Poster Presentation

Recommended citation: Saifullah, K., et al. Plasma Neurofilament Light Reflects Brain Tissue Loss, Ventricular Enlargement, and Vascular-Mediated Neurodegeneration. Poster Presentation, Radiological Society of North America (RSNA), 111th Scientific Assembly and Annual Meeting, Nov 30 - Dec 4, 2025, Chicago, IL, USA.

ARTS is associated with NfL but not with p-Tau217

Published in Alzheimer’s Association International Conference (AAIC), 2025

Poster Presentation

Recommended citation: Chowdhury, G. M., Saifullah, K., et al. ARTS is associated with NfL but not with p-Tau217. Poster Presentation, Alzheimer’s Association International Conference (AAIC) Annual Meeting, July 27-31, 2025, Toronto, Canada.
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Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities

Published in Alzheimer's Association International Conference (AAIC), 2025

Poster Presentation

Recommended citation: Saifullah, K., et al. Plasma Neurofilament Light Links to Brain Tissue Loss, Ventricular Enlargement, and Elevated White Matter Hyperintensities. Poster Presentation, Alzheimer’s Association International Conference (AAIC) Annual Meeting, July 27-31, 2025, Toronto, Canada.
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Elevated ARTS Scores Correlate with Increased NfL Levels but Not p-Tau217

Published in Organization for Human Brain Mapping (OHBM), 2025

Poster Presentation

Recommended citation: Chowdhury, G. M., Saifullah, K., et al. Elevated ARTS Scores Correlate with Increased NfL Levels but Not p-Tau217. Poster Presentation, Organization for Human Brain Mapping (OHBM) Annual Meeting, June 24-28, 2025, Brisbane, Australia.

Plasma Neurofilament Light is associated with less brain tissue, larger ventricles, and higher white matter hyperintensities volume

Published in International Society for Magnetic Resonance in Medicine (ISMRM), 2025

Poster Presentation

Recommended citation: Saifullah, K., et al. Plasma Neurofilament Light is associated with less brain tissue, larger ventricles, and higher white matter hyperintensities volume. Poster Presentation, ISMRM & ISMRT Annual Meeting & Exhibition, May 10-15, 2025, Honolulu, Hawaiʻi, USA.
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Brain atrophy in Alzheimer’s and LATE neuropathology

Published in Radiological Society of North America (RSNA), 2024

Poster Presentation

Recommended citation: Saifullah, K., et al. Brain atrophy in Alzheimer’s and LATE neuropathology. Poster Presentation, Radiological Society of North America (RSNA), 109th Scientific Assembly and Annual Meeting, Dec 1-5, 2024, Chicago, IL, USA.

Spatial pattern of brain atrophy in Alzheimer’s and LATE neuropathology

Published in Organization for Human Brain Mapping (OHBM), 2024

Poster Presentation

Recommended citation: Saifullah, K., et al. Spatial pattern of brain atrophy in Alzheimer’s and LATE neuropathology. Poster Presentation, Organization for Human Brain Mapping (OHBM) Annual Meeting, June 23-27, 2024, Seoul, Korea.

Subcortical shapes and age-related neuropathologies

Published in Organization for Human Brain Mapping (OHBM), 2023

Poster Presentation

Recommended citation: Saifullah, K., Makkinejad, N., et al. Subcortical shapes and age-related neuropathologies. Poster Presentation, Organization for Human Brain Mapping (OHBM) Annual Meeting, July 22-26, 2023, Montréal, Canada.

Associations of subcortical shapes with age-related neuropathologies in community-based older adults

Published in Alzheimer's Association International Conference (AAIC), 2023

Poster Presentation

Recommended citation: Saifullah, K., Makkinejad, N., et al. Associations of subcortical shapes with age-related neuropathologies in community-based older adults. Poster Presentation, Alzheimer's Association International Conference (AAIC) Annual Meeting, July 16-20, 2023, Amsterdam, Netherlands.
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Associations of the shape of subcortical brain structures with age-related neuropathologies in community-based older adults

Published in International Society for Magnetic Resonance in Medicine (ISMRM), 2023

Poster Presentation

Recommended citation: Saifullah, K., Makkinejad, N., et al. Associations of the shape of subcortical brain structures with age-related neuropathologies in community-based older adults. Poster Presentation, ISMRM & ISMRT Annual Meeting & Exhibition, June 3-8, 2023, Toronto, Canada.
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Towards Classification of Neurofibrillary Tangles with MRI-Based Biomarker

Published in Radiological Society of North America (RSNA), 2022

Oral Presentation

Recommended citation: Saifullah, K., et al. Towards Classification of Neurofibrillary Tangles with MRI-Based Biomarker. Radiological Society of North America (RSNA), 108th Scientific Assembly and Annual Meeting, Oral Presentation, Nov 27 - Dec 1, 2022, Chicago, IL, USA.

Neurofibrillary Tangles Prediction Based on MRI

Published in Alzheimer's Association International Conference (AAIC), 2022

Oral Presentation

Recommended citation: Saifullah, K., et al. Neurofibrillary Tangles Prediction Based on MRI. Alzheimer’s Association International Conference (AAIC), Oral Presentation, July 31 - Aug 4, 2022, San Diego, CA, USA.
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MRI-based Neurofibrillary Tangles Prediction

Published in Organization for Human Brain Mapping (OHBM), 2022

Poster Presentation

Recommended citation: Saifullah, K., et al. MRI-based Neurofibrillary Tangles Prediction. Poster Presentation, Organization for Human Brain Mapping (OHBM) Annual Meeting, June 19-23, 2022, Glasgow, Scotland.

Towards an MRI-based Prediction of Neurofibrillary Tangles

Published in International Society for Magnetic Resonance in Medicine (ISMRM), 2022

Oral Presentation

Recommended citation: Saifullah, K., et al. Towards an MRI-based Prediction of Neurofibrillary Tangles. ISMRM-ESMRMB & ISMRT Joint Annual Meeting, Oral Presentation, May 7-12, 2022, London, UK.
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